| IBIOM |
(+)RNA virus replication-associated protein expression in Saccharomyces cerevisiae
| yeast, (+)RNA virus, SARS-CoV-2, cell membranes | G. Petrosillo, N. Guaragnella, C. Musicco, F. Mastrorocco, S. Giannattasio |
| ITB |
A drug repositioning pipeline to evaluate a synergic effect of small molecules on CFTR drugs
| Cystic fibrosis, Drug repositioning, pipeline, drug discovery and bioinformatics | P. D’Ursi, A. Orro |
| IRIB |
A METHODOLOGICAL FRAMEWORK TO DISCOVER PHARMACOGENOMIC INTERACTIONS BASED ON RANDOM FORESTS
| cancer; drug response; genomic alterations; pharmacogenomic interactions | S. Fasola, S. La Grutta |
| IBPM |
A novel approach to modulate the protein levels of the spastin enzyme acting on Cullin4mediated degradation: from molecular mechanisms to therapy
| spastin; Hereditary Spastic Paraplegia (HSP); poly-ubiquitylation/degradation; neddylation inhibitor; Cullin-4-Ring ubiquitin ligase complex (CRL4) | F. Sardina, C. Carsetti, M. Pisa, G. Cestra, C. Rinaldo |
| IGM |
A novel approach to telomere-driven cellular senescence and age-related diseases
| aging, telomeres, ncRNA, ASO | F. d’Adda di Fagagna |
| IBB |
A Reversible Shift of Driver Dependence from EGFR to Notch1 in Non-Small Cell Lung Cancer as a Cause of Resistance to Tyrosine Kinase Inhibitors
| Notch1, EGFR, EMT, tumor spheres, NSCLC | F. Iommelli, V. De Rosa, R. Fonti |
| IBIOM |
A yeast model to unravel new BRCA2 functions in cell stress response and metabolism
| cancer, BRCA2, yeast, cell death, metabolic reprogramming | A. Costanza, N. Guaragnella, A. L'Abbate, C. Musicco, F. Mastrorocco, E. Picardi, A. M. D'Erchia, G. Pesole, S. Giannattasio |
| IBPM |
AAV mediated delivery of artificial transcription factor genes as therapeutic strategy for Duchenne Muscular Dystrophy
| AAV, zinc finger artificial transcription factor, DMD, utrophin, NMJ | C. Pisani |
| IBBC |
APPLICATION OF CRISPR/CAS9 STRATEGY FOR GENE THERAPY OF INHERITED DISEASES
| gene therapy, CRISPR/Cas9, myotonic dystrophy type 1 | B. Cardinali, C. Provenzano, M. Izzo, J. Battistini, G. Strimpakos, E. Golini, S. Mandillo, F. Scavizzi, M. Raspa, G. Falcone |
| IBFM |
Assessment of radiotherapy efficacy in a GBM-immunocompetent animal model
| GBM, radiotherapy, in vivo imaging, tumor microenvironment, tumor response/resistance | S. Valtorta, G. Bertoli, S. Todde, S. Belloli, R. M. Moresco |
| IBIOM |
Bioinformatics approaches for COVID-19 genomics
| Bioinformatics; Comparative Genomics; Variant Prioritization; Big Data; COVID-19 | M. Chiara, E. Ferrandi, P. Mandreoli, M. A. Tangaro, G. Pesole |
| IBPM |
BLOCKAGE OF AUTOPHAGOSOME-LYSOSOME FUSION THROUGH SNAP29 INHIBITION PROMOTES APOPTOSIS VIA ROS PRODUCTION
| mitosis, kinetochore, autophagy, anticancer therapy, SNAP29 | F. R. Pellegrini, S. De Martino, I. Ventura, M. Fiore, D. Trisciuoglio, F. Degrassi |
| IBF |
Breaking the code of ribosome heterogeneity to develop next-generation non-coding RNA-based therapies
| Ribosome; post-transcriptional modification; RNA-therapy; ribosome profiling; genetic diseases | F. Lauria, D. Donzel, I. Signoria, G. Viero |
| IFC |
Cancer genomics through Third Generation Sequencing of cell free DNA from liquid biopsy
| Copy Number Aberrations, Cancer, Plasma, Epigenetics, Circulating tumor DNA | S. G. Conticello |
| IBF |
Computational Neuroscience for Drug Discovery
| brain diseases, ageing, modeling, drug discovery, EBRAINS | M. Migliore |
| IGB |
CRISPR correction of DNMT3B mutations in ICF1 patient iPSCs identifies early genomic disease targets with restored DNA methylation
| DNA methylation, patient-iPSCs, ICF syndrome, DNMT3B, hematopoietic progenitors | M. Strazzullo, V. Poondi-Khrishnan, B. Morone, L. Pisapia, M.R. Matarazzo |
| IBIOM |
DETECTION OF THE MOLECULAR TARGETS OF METFORMIN AND CURCUMIN. A NEW COMBINATION FOR CANCER THERAPY?
| metformin; curcumin; mitochondrial respiratory chain complexes; glycolysis; glyoxalase system | L. de Bari, M. F. Caratozzolo |
| IBPM |
Developing protein-protein interaction inhibitors to target oncogenic functions of the Aurora-A kinase
| Aurora-A, TPX2, MYCN, cancer, protein-protein interaction inhibitors | I.A. Asteriti, F. Polverino, G. Colotti, G. Guarguaglini |
| IN |
Development of a novel photothrombotic model in mice to reproduce human malignant stroke
| Brain, Stroke, Translational stroke research, Reperfusion | M. Baldereschi |
| IEOS |
DEVELOPMENT OF APTAMER-CONJUGATED POLYMER NANOPARTICLES FOR SELECTIVE PHOTODYNAMIC THERAPY OF TRIPLE-NEGATIVE BREAST CANCER CELLS
| conjugated polymer nanoparticles, photodynamic therapy, aptamers, TNBC | L. E. Ibarra, S. Camorani, L. Agnello, A. D'Argenio, R. Nilo, M. Fedele, L. Cerchia |
| IEOS |
DEVELOPMENT OF INNOVATIVE DRUG-LOADED AND APTAMER TARGETED NANOSYSTEMS FOR TREATMENT OF TRIPLE-NEGATIVE BREAST CANCER
| Nucleic acid aptamers, precision nanomedicine, targeted drug delivery, TNBC, cancer immunotherapy | S. Camorani, L. Agnello, S. Tortorella, L. E. Ibarra, A. d'Argenio, R. Nilo, M. Fedele, L. Cerchia |
| IBBC |
Development towards clinical application of the anticancer peptide Pep3 for reactivation of p53
| p53, MDM4-MDM2 heterodimer, peptide-based therapeutic, PLGA, NSCLC | M.R. Assenza, L. Giorgini, S. Valentini, M. Attili, S. Maiullari, M. Raspa, F. Scavizzi, F. Moretti |
| IBPM |
Dissecting how microenvironment remodelled by tumor and stromal cells facilitate ovarian cancer metastasis: interaction between endothelin and integrin signaling
| cancer/stroma, invadopodia, GPCR, integrin, organotypic model | I. Masi, D. Del Rio., F. Ottavi, L. Rosanò |
| IBPM |
Dissecting the role of the oncoprotein GOLPH3 in cytokinesis and cell proliferation
| GOLPH3, Golgi, cytokinesis, cancer, Drosophila | A. Frappaolo, S. Sechi, A. Karimpour-Ghahnavieh, M .G. Giansanti |
| IEOS |
DNA Methylation and Type 2 Diabetes: Novel Biomarkers for Risk Assessment?
| biomarkers of risk assessment; DNA methylation; First-degree-relatives of type 2 diabetes; TXNIP (cg19693031) | P. Mirra, L. Parrillo, C. Nigro, C. Miele |
| IRGB |
Estradiol treatment as therapeutic strategy for Cornelia de Lange syndrome
| Cornelia de Lange syndrome, c-MYC, gene expression dysregulation, estradiol, cohesin | A. Musio |
| IBB |
Exploring brain microstructure by Quantitative Magnetic Resonance Imaging
| Relaxometry, quantitative MRI, magnetic susceptibility, tissue microstructure | S. Monti |
| IBIOM |
Glutamine traffic: link with cancer and drug targeting
| glutamine; cancer; drug target; drug design; membrane transport | C. Indiveri, A. Tonazzi, N. Giangregorio |
| IFC |
HEALTH360: A CLOUD-BASED TOOL FOR DATA COLLECTION LEADING TO PRECISION MEDICINE IN NEUROMUSCULAR DISORDERS
| cloud, ICT, neuromuscular disorders, p4 medicine, software | R. Conte, A. Tonacci |
| IBBC |
Human Paraoxonase-2 (PON2): role in cancer and more
| PON2; anti-redox activity; anti-apoptosis; cancer; mRNA regulation | E. Porzio, T. M. Carusone, M. Marone, G. Manco |
| IGM |
Human RNA helicase DDX3X as a target for broad spectrum antiviral agents
| virtual screening, host-pathogen interactions, antiviral drug, cellular target, RNA helicase | G. Maga |
| IBB |
Hunting for new therapeutics against antibiotic resistant pathogens
| Protein structure, emerging infections, therapeutic development, RNA | F. Squeglia, M. Romano, A. Ruggiero, R. Berisio |
| IBPM |
IDENTIFICATION OF PATHOLOGICAL NONCODING RNAS AS NEW TARGETS FOR RNA-MEDIATED THERAPIES IN BRAIN CANCER
| Medulloblastoma; long noncoding RNAs; cancer driver genes; competing endogenous RNAs; MYC | P. Laneve , J. Rea, B. Illi, D. Trisciuoglio, E. Caffarelli |
| IBPM |
In silico design and evaluation of exon skipping-inducing antisense oligonucleotides for therapeutic intervention in rare cancers
| cancer; exon-skipping; genomics; precision medicine; rare diseases | V. Morea, A. Via, T. Colombo |
| IBBC |
Inhibition of osteoclast activity by G-protein-coupled receptor targeting
| G-protein-coupled receptors, osteoclastogenesis, allosteric antagonism, peptidic binders | M. G. Mosca, R. D'Angelo, S. Mariggiò |
| IBBC |
Intracerebellar administration of the chemokine Cxcl3 prevents the neoplastic transformation of cerebellar precursor cells forcing their migration
| Medulloblastoma; Mouse model; Cxcl3; Migration; Preneoplastic lesions | M. Ceccarelli, L. Micheli, G. D’Andrea, F. Tirone |
| IGM |
Leveraging chromatin 3D architecture to understand unexplained clinical heterogeneity
| Chromatin 3D architecture, Computational genomics, Gene regulatory networks, Epigenetics, Cancer | F. Ferrari |
| IFC |
Lmat≡LNA-204 as therapeutic strategy in melanoma
| LNA-204 inhibitor, apoptosis, in vivo melanoma models, attenuated Listeria monocytogenes, click chemistry | L. Poliseno |
| IBIOM |
Machine Learning approaches for the investigation of the human microbiome
| human gut microbiome, machine learning, GMHI | B. Fosso, M. A. Tangaro, G. Defazio, G. Pesole |
| IBB |
Machine Learning for Clinical Radiobiology
| Outcome modelling, Voxel-Based Analysis, radiation-induced morbidity, treatment personalization | L. Cella, S. Monti |
| IFC |
MAPK15 Controls Hedgehog Signaling in Medulloblastoma Cells by Regulating Primary Ciliogenesis
| MAP kinases; primary cilia; cancer stem cells; medullo-spheres; GLI1 | S. Pietrobono, L. Franci, F. Imperatore, M. Chiariello |
| IFC |
MAPK15 Protects from Oxidative Stress-Dependent Cellular Senescence by Inducing the Mitophagic Process
| MAP kinases; mitochondria; Reactive Oxygen Species; Aging; Mitophagy | L. Franci, M. Chiariello |
| IBIOM |
Microbiome studies in female upper reproductive tract
| Microbiome, endometrium, ovarian cancer, metabarcoding, metagenomics | C. Leoni, C. Manzari, B. Fosso, M. Volpicella, G. Pesole, L. R. Ceci |
| IN |
miR-150-5p AND let-7b-5p IN BLOOD MYELOID EXTRACELLULAR VESICLES TRACK COGNITIVE SYMPTOMS IN MULTIPLE SCLEROSIS PATIENTS
| Multiple Sclerosis; cognitive deficits; extracellular vesicles; miRNAs; myeloid cells | M. Gabrielli |
| IFC |
miRNAs released by prostate cancer cells resistant to docetaxel play a role in the resistance mechanism and act as predictive biomarkers
| prostate cancer, miRNAs, docetaxel, drug resistance, circulating miRNAs biomarkers | M. Canovai, M. Evangelista, A. Mercatanti, M. Rizzo |
| IBPM |
Mitoxantrone-loaded nanoferritin slows tumor growth and improves the overall survival rate in a subcutaneous pancreatic cancer mouse model
| Targeted therapy; Pancreatic Cancer; human ferritin; transferrin receptor (CD71); Mitoxantrone | P. Ceci, E. Falvo |
| IBBC |
MODULATION OF INNATE IMMUNE MEMORY: A NEW PERSPECTIVE IN THE PERSONALIZED BIOMEDICAL APPLICATION OF NANOPARTICLES
| nanoparticles, innate immune memory, monocytes | A. Corteggio, T. Heinzl, D. Melillo, P. Italiani |
| IRGB |
Modulation of miR-181a/b ameliorates mitochondrial-mediated neurodegeneration
| MicroRNA, Mitochondrial Diseases, Neurodegeneration, Gene therapy, RNA-therapy | A. Indrieri |
| IGB |
mRNA Analysis of Frameshift Mutations with Stop Codon in the Last Exon
| unstable α‐Hb variants; dominant phenotype; mRNA quality control; Nogo decay; in silico analysis | R. Prezioso, G. Cardiero, G. Lacerra |
| IBPM |
New cellular imaging-based biomarkers for neurodegenerative diseases (ND) in the era of precision medicine
| cellular imaging-based test; biomarker; neurodegeneration; spastin; cytoskeleton | C. Rinaldo, G. Fattorini, R. Caizzi, F. Sardina |
| IFC |
New Chitosan B-glycerophospate gel-based formulations enhance Temozolomide availability for local in vivo treatment of glioblastoma
| Precision medicine, SiO2 colloids, Thermogel, preclinical investigation, drug delivery | L. Gherardini, M. Chiariello |
| IBPM |
NITRIC OXIDE HITS GLIOBLASTOMA STEM CELLS BY INDUCING DNA DAMAGE AND TEMOZOLOMIDE SENSITIZATION
| Glioblastoma stem cells, Nitric oxide, Temozolomide, DNA damage, adjuvant treatment | L. Salvatori, S. Malatesta, M. P. Somma, B. Illi |
| IBB |
Non-canonical role of PDK1 as a negative regulator of apoptosis through macromolecular complexes assembly at the ER-mitochondria interface in oncogene-driven NSCLC
| PDK1; OXPHOS; glycolysis; apoptosis; drug resistance | V. De Rosa, F. Iommelli |
| IBPM |
Nucleolar G-quadruplexes as targets in anti-cancer therapy
| G-quadruplex, rRNA, nucleolus | E. Vertecchi, E. Salvati |
| IBPM |
Ovarian cancer-driven mesothelial-to-mesenchymal transition is triggered by the endothelin-1 axis
| stroma, mesothelial cells, endothelin, mesothelial-to-mesenchymal transition, ovarian cancer | D. Del Rio, I. Masi, F. Ottavi, L. Rosanò |
| IEOS |
PARP10-Aurora A cross-talk in the regulation of cell cycle
| mono-ADP-ribosylation, cell cycle, cancer | G. Grimaldi, M. Matarese, N. Dathan, S. Di Paola |
| IBPM |
Pathogenic epigenetic reprogramming of stromal cells contributes to adverse cardiac remodeling
| cardiac stromal cells, cardiomyopathy, epigenetics, Fibro-adipogenic progenitors | V. Bianconi, R. Didonna, C. Mozzetta |
| IRGB |
PBX1-directed stem cell transcriptional program drives tumor progression in myeloproliferative neoplasm
| myeloid neoplasm; MPN; hematopoietic stem cells; PBX1; JAK2 | F. Ficara |
| ITB |
Potential new therapies targeting NSCLC heterogeneity
| NSCLC, high-resolution transcriptomics, murine models, cancer stem cell therapy, immunotherapy | E. Levantini, G. Maroni, M. C. Magli |
| IGM |
Prelamin A as a therapeutic target in premature ageing syndromes
| Prelamin A, Ageing, Hutchinson-Gilford Progeria, Tocilizumab, Therapeutic targets | G. Lattanzi |
| IEOS |
Prioritization of driver genes in cancer-associated copy number alterations identifies B4GALT5 as a glycooncogene
| cancer, copy number alterations, glycosylation, Golgi apparatus | F. Russo, P. Sahu, I. Agliarulo, F. Carlomagno, A. Luini, S. Parashuraman |
| IEOS |
Protein mono-ADP-ribosylation in the control of cell physio-pathology
| mono-ADP-ribosylation; membrane transport; cancer; viral infection | S. Di Paola, A. Pavithran, M. Matarese, N. Dathan, G. Grimaldi |
| IEOS |
Q2 derivative prevents obesity by inducing browning and inhibiting adipogenesis of 3T3-L1 adipocytes
| Obesity, Browning, Adipogenesis, Quercetin | P. Ungaro |
| IFC |
Radiobiological evaluation of Laser-accelerated Very High-Energy Electrons (VHEE) for FLASH radiotherapy: Study design and preliminary findings
| VHEE, plasma-laser accelerator, FLASH radiotherapy, radiobiological response, cytokinesis-block micronucleus assay | A. Borghini, D. Panetta, A. Mercuri, S. Turchi, M. G. Andreassi |
| IGM |
Reduced levels of Prostaglandin I2 Synthase: a distinctive feature of the cancer-free trichothiodystrophy
| nucleotide excision repair (NER); NER-defective disorders; TFIIH; Transcription; PTGIS | D. Orioli |
| ITB |
Role of genome structure in prostate cancer
| Epigenetics, chromatin compartment, nuclear structures, genome function, prostate cancer | C. Lanzuolo |
| IBPM |
Role of PRDM16 in maintaining nuclear integrity and genomic stability in fibro-adipogenic progenitors
| epigenetics, muscle dystrophy, tumors | A. Guidi, F. Guarino, V. Bianconi, F. Polverino, G. Guarguaglini, C. Mozzetta |
| IBIOM |
Role of TRIM8 in p53-dependent regulation of the expression of genes involved in the transport of chemotherapeutic drugs
| p53, TRIM8, chemoresistance | F. Marzano, A. Amendolare, M. F. Caratozzolo, G. Pesole, A. Tullo |
| IBPM |
Selective inhibition of CBP/p300 drives a redox/autophagy/senescence axis leading to cell death in non-small cell lung cancer cells
| Histone acetyltransferases, autophagy, senescence, oxidative stress | M. S. Z. Ansari, V. Stagni, A. Iuzzolino, F. Degrassi, D. Trisciuoglio |
| IEOS |
SERS Quantification and efficient delivery of Galunisertib in living Colorectal Cancer Cells by Diatomite Nanoparticles
| Cancer, drug delivery, SERS, Imaging | S. Managò, A. C. De Luca |
| IBB |
Structural insights into the inhibition mechanism of hCA XII by a theranostic monoclonal antibody fragment
| anticancer drugs; carbonic anhydrase XII complex; crystal structure; monoclonal antibody | V. Alterio, D. Esposito, S. M. Monti, G. De Simone |
| IBBC |
TARGETED BACTERIOPHAGE NANOPARTICLES FOR ANTICANCER IMMUNOTHERAPY
| antigen delivery; filamentous bacteriophage; programmed death-ligand 1, cell targeting; anti-tumor immunity | R. Sartorius, L. D'Apice, M. Trovato, R. Manco, P. De Berardinis |
| IRGB |
TARGETED GENOME EDITING OF HAEMATOPOIETIC STEM CELLS FOR TREATING RECOMBINATION ACTIVATING GENE 1 (RAG1) IMMUNODEFICIENCY
| Gene editing, Immunodeficiency, RAG1, Haematopoietic stem/progenitor cells | M. C. Castiello |
| IRIB |
TARGETING ALPHA ENOLASE-HSP70 COMPLEXES TO COUNTERACT THE METASTATIC POTENTIAL OF CANCER CELLS
| ENO1, HSP70, protein-protein interaction, computational approaches, cell migration | G. Perconti |
| IBB |
Targeting hypoxia-induced carbonic anhydrases 9 improves response to cisplatin treatment in head and neck squamous carcinoma
| Tumor microenvironment, hypoxia, drug resistance, Head and Neck Squamous Carcinoma, carbonic anhydrase 9 | A. Sarnella, Y. Ferrara, L. Auletta, S. Albanese, V. Alterio, G. De Simone, A. Zannetti |
| IEOS |
Targeting of Cancer associated fibroblast in NSCLC by new aptamer-based approaches
| Aptamers, SELEX, CAFs, NSCLC, Targeted delivery | M.L. Ibba, G. Coppola, G. Petrillo |
| IFT |
Targetting proNGF/p75NTR axis as a novel treatment for chronic arthritis
| Chronic inflammatory diseases, p75NTR inhibition, inflammation, rheumatoid and juvenile idiopathic arthritis, cytokines | L. Bracci-Laudiero, L. Manni, M. Soligo |
| IBPM |
THE CDK4/6 INHIBITOR PALBOCICLIB INDUCES REVERSIBLE SENESCENCE IN BREAST CANCER CELLS
| Senescence, Palbociclib, Inflammation, Immunotherapy | F. Antonangeli, G. Favaretto |
| IGM |
The dark side of IFN-γ in acute myeloid leukemia
| IFN-γ, acute myeloid leukemia, leukemic microenvironment, regulatory T cells, stromal microenvironment | M. Ciciarello |
| IFC |
The FHP01 DDX3X Helicase Inhibitor Exerts Potent Anti-Tumor Activity In Vivo in Breast Cancer Pre-Clinical Models
| Triple negative breast cancer, DDX3X helicase, in-silico design, preclinical investigation, target therapy | L. Gherardini, M. Chiariello |
| IEOS |
The glycerophosphoinositols: from physiology to pharmacology
| Glycerophosphoinositols, Shp1, target identification | A. Varone, M. Monti |
| IBBC |
The new PI3K inhibitor MEN1611 strongly counteracts tumor growth in the high frequency medulloblastoma mouse model Ptch1+/−/Tis21KO
| Medulloblastoma; Mouse model; Allograft model; PI3K/AKT/mTOR pathway; MEN1611 | M. Ceccarelli, G. D’Andrea, L. Micheli, G. Papoff, F. Tirone |
| IFC |
The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males
| SARS-CoVC-2; Toll-like Receptors; Autophagy; Chloroquine | F. Imperatore, M. Chiariello |
| IBPM |
The RNA helicase DDX5 cooperates with EHMT2 to sustain alveolar rhabdomyosarcoma growth
| cancer epigenetics, RNA helicase, DDX5, rhabdomyosarcoma, EHMT2 | V. Bianconi, A. Gualtieri, C. Mozzetta |
| IRGB |
TOWARDS THE CLINICAL TRANSLATION OF LENTIVIRAL VECTOR GENE THERAPY FOR OSTEOPETROSIS
| osteopetrosis, osteoclast, gene therapy, lentiviral vector, hematopoietic stem cells | V. Capo |
| IFC |
Transcriptome profiling of RPE cells to unravel new MAPK15 biological functions
| RNA-seq, transcriptome, kinase, autophagy | D. Tatoni, F. Imperatore, L. Franci, M. Chiariello |
| ITB |
Transmembrane Protein TMEM230, a target for vascular regeneration and treament for highly vascularized tumors
| Vascular regeneration; Tumor treatment; Glioblastoma; Vascular normalization; Tumor associated angiogenic switch | C. Cocola, I. Zucchi, R. Reinbold |
| IBPM |
Trypanothione Reductase: one target, different approaches for the development of a broad-spectrum trypanocidal drug
| Leishmaniasis, Trypanothione Reductase, Structural Biology, Structure-Based Drug Design | A. Fiorilloa, C. Exertier, G. Colotti, A. Ilari |
| IBF |
Type I and II BIR domains as targets for cancer therapy
| Drug discovery, Apoptosis, NF-κB, IAPs, Smac-mimetics | F. Cossu, M. Milani, T. Giorgino, E. Mastrangelo |
| IGB |
Ultraconserved Region Encoding ncRNAs involvement in Bladder tumors
| Bladder cancer; prognostic biomarker; Transcribed-ultraconserved region; long noncoding RNA; ultraconserved transcript 8+ (uc.8+) | A. Cimmino, G. Del Pozzo, V. Mercadante, G. L. Liguori, V. Costa |
| IFC |
Unraveling the biology of BRAFV600E isoforms in melanoma
| BRAFV600E isoforms, yeast genome-wide screening, zebrafish, autophagy, de novo fatty acid synthesis | T. Cervelli |
| IFC |
Validation of three yeast-based assays for functional classification of BRCA1 missense variants: application of Machine Learning methods
| S. cerevisiae, functional assay, BRCA1 VUS, DNA repair, machine learning | T. Cervelli |
| IN |
Viral delivery of a SOX2 engineered epigenetic silencer factor in glioblastoma represses the cancer genetic program and restrains tumor development
| Glioblastoma, CSCs, SOX2, Epigenetics, Gene therapy | V. Benedetti, F. Banfi, V. Broccoli |