Institute of Protein Biochemistry, CNR.

Via P. Castellino, 111 - 80131 Napoli

2014 IBP Seminar Series

CNR Conference Room

Tuesday, July 8th, 2014 at 14:00

Dr. Anna Rubartelli

IRCCS AOU San Martino, IST-National Institute for Cancer Research, Genova, Italy

"Stress control of IL-1beta processing and secretion: consequences on the inflammatory response"

Host: Dr Diana Boraschi

Tel. 081-6132623; e-mail: d.boraschi@ibp.cnr.it

Dr Rubartelli is an expert of inflammation and innate immune response. Her key scientific achievements include the identification of a leaderless secretory pathway for secretory proteins lacking signal sequences in the early '90s. In particular, her studies focused on proteins involved in inflammation, such as Interleukin-1beta, IL-18, thioredoxin and HMGB1. Later on, she got involved in the study of the redox response to stress, in acute and chronic inflammation. The results obtained, translated to the study of pathologic conditions such as autoinflammatory and autoimmune syndromes, and cancer, allowed to clarify several aspects of the pathogenesis of these diseases. 

Dr Anna Rubartelli received her Doctor of Medicine magna cum laude in 1981 at the University of Genoa, Italy, and completed her specialist training in Clinical and Experimental Hematology at the same University. Currently, she is the Director of the Cell Biology Unit at the IRCCS San Martino IST National Institute for Cancer Research, Genova, Italy. 

Rubartelli is an Associate Editor for Frontiers of Inflammation and European Journal of Immunology. She is author of numerous scientific papers on high ranked international journals, and of several articles on Books.

Dr Maria Rosaria Coscia & Stefania Mariggiò
Seminar Coordinators
Institute of Protein Biochemistry, CNR
Via P. Castellino, 111
80131 Naples Italy
Tel 0039 081 6132556/545