Institute of Protein Biochemistry, CNR.

Via P. Castellino, 111 - 80131 Napoli

2014 IBP Seminar Series

CNR Conference Room

Friday, June 20th, 2014 at 14:30

Prof. Robert M. Brosh

National Institute on Aging, National Institutes of Health
NIH Biomedical Research Center, Baltimore, USA

"DNA Helicases and their roles in cancer, genetic diseases, and aging"

Host: Dr Francesca M. Pisani

Tel. 081-6132292; e-mail: fm.pisani@ibp.cnr.it

Helicases are molecular motors that catalytically unwind structured nucleic acids in an ATP-dependent manner. The growing number of DNA helicases implicated in hereditary diseases and cancer strongly suggest that these enzymes have vital specialized roles in cellular pathways important for the maintenance of chromosomal integrity. Brosh’s group, the Section on DNA Helicases of the National Institute on Aging, NIH, investigates the involvement of helicases in nuclear and mitochondrial genome stability at the cellular and molecular level.

Dr Maria Rosaria Coscia & Stefania Mariggiò
Seminar Coordinators
Institute of Protein Biochemistry, CNR
Via P. Castellino, 111
80131 Naples Italy
Tel 0039 081 6132556/545